Lung Cancer Pneumonectomy

A pneumonectomy allows doctors to extract a lung and cancer tumors within the thoracic (chest) cavity. While it is a very intense procedure, a pneumonectomy for lung cancer can help many patients live longer. Learn more about this lung removal surgery, its benefits, side effects, costs, and more below.

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What Is Pneumonectomy for Lung Cancer?

A pneumonectomy for lung cancer is a surgery to remove one of your lungs. It is the most aggressive type of lung resection or surgery.

There are two main types of pneumonectomy procedures:

  • A simple or standard pneumonectomy is a surgical resection removing your entire right or left lung and, sometimes, nearby tissue and nerves.
  • An extrapleural pneumonectomy (EPP) involves removing your lung, pleura (lung lining), pericardium (heart lining), and parts of your diaphragm (the muscle under your lungs).

Since it involves removing a patient’s lung, a pneumonectomy has a high risk of complication and is typically only recommended as a last resort. However, some patients can become long-term survivors following this procedure.

Skilled doctors can determine if a pneumonectomy or another lung cancer surgery could benefit you or someone you love.

Learn more about surgeries and other types of treatment that can help you or a loved one in our Free Lung Cancer Guide.

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Who Is Eligible for a Lung Cancer Pneumonectomy?

You may be eligible for a lung cancer pneumonectomy if you meet several criteria related to your diagnosis and health.

These include:

  • Being in overall good health: To safely undergo a pneumonectomy, doctors will need to make sure that you can have a good quality of life with only one lung. They will also check if you have other health problems that could increase your risk of complications.
  • Being younger: Younger lung cancer patients are typically physically stronger and have a better chance of recovering without complications.
  • Having cancer that is only in the lung: If doctors find evidence of metastasis (cancer spread) outside of just one lung, they will likely recommend other treatments.
Did You Know?

Most patients who receive pneumonectomies have non-small cell lung cancer (NSCLC). By contrast, small cell lung cancer (SCLC) patients usually can’t undergo pneumonectomies or other surgeries due to cancer spread.

Those with pleural mesothelioma (cancer of the lung lining) may also be eligible to get a pneumonectomy. Patients who undergo a mesothelioma pneumonectomy and other treatments live for 35.6 months on average.

Talk to your oncology (cancer care) team to see if you qualify for lung removal surgery. If you are not eligible, your doctor can suggest other treatments that may allow you to live longer.

Pneumonectomy vs. Other Types of Lung Cancer Surgery

Pneumonectomy is the most aggressive type of lung cancer surgery. Most doctors will recommend a less extensive surgery in which only part of a lung is removed if possible. This way, patients can often recover faster and more easily.

Here’s how pneumonectomy compares to other lung cancer surgeries:

  • Bronchial sleeve resection may be used to treat cancer in the lungs’ large airways and lung lobe(s). It involves removing the part of the main airway (bronchus) with a tumor and reattaching the healthy ends of the bronchus.
  • Segmentectomy or wedge resection only removes part of a lung lobe. Doctors may suggest this approach if a patient does not have enough lung function to undergo a lobectomy or pneumonectomy.
  • Lobectomy removes the entire lobe containing the lung tumor. The right lung has three lobes, and the left has two.

“For most lung cancers, pneumonectomy isn’t the right option, and in some cases, patients may not have enough lung function to accommodate an entire lung being removed.”
— Cancer hospital network City of Hope

Lung cancer doctors can determine which type of surgery will be best for your case.

How Do Lung Cancer Pneumonectomies Work?

Doctors follow a series of steps to perform a lung cancer pneumonectomy.

These steps include:

  1. Assessment: Doctors will have the patient undergo cardiovascular and respiratory tests to determine if a lung cancer pneumonectomy is the best surgery for them.
  2. Chemotherapy: According to City of Hope, many pneumonectomy patients receive chemotherapy before surgery. Chemotherapy helps to shrink the tumors so they can be removed more easily.
  3. Anesthesia: When it’s time for your pneumonectomy, you’ll go to the hospital and be placed under anesthesia so you won’t feel anything.
  4. Pneumonectomy: Doctors will deflate your lung and remove it using either video-assisted thoracic surgery (VATS) or a thoracotomy (a surgical procedure involving an incision between the ribs to reach the chest cavity). They may also extract the pleura, diaphragm, pericardium, and/or lymph nodes.
  5. Recovery: You’ll awaken from anesthesia and spend several days recovering in the hospital. You’ll be guided through the recovery process by your medical team and monitored for complications.

Call (877) 446-5767 for help exploring lung cancer treatment options like a pneumonectomy and pursuing compensation for medical expenses.

Recovering From Lung Cancer Pneumonectomy

Recovering from a lung cancer pneumonectomy generally requires 2 weeks in the hospital and 6 to 8 weeks at home. You may be sore and experience shortness of breath as you heal.

It is important to follow your health care provider’s recommendations for a healthy and quick recovery.

These may include:

  • Adjusting your lifestyle to optimize your lung function
  • Avoiding lung irritants like secondhand smoke and dust
  • Getting pulmonary rehabilitation (a supervised medical program that helps people improve their breathing)
  • Resting as much as possible

During regular follow-up appointments, your medical team will address any complications or side effects and monitor your lung function.

Johns Hopkins Medicine also notes that most patients don’t feel severe pain following a pneumonectomy, though you’ll be sore afterward.

Lung Cancer Pneumonectomy Prognosis

Prognosis measures a patient’s expected health outlook. The lung cancer prognosis following a pneumonectomy is favorable if there are minimal complications.

Lung cancer prognosis is measured by:

  • Life expectancy: This is the patient’s projected survival time. The median life expectancy for patients who underwent a lung cancer pneumonectomy is 47 months, according to an Interactive Cardiovascular and Thoracic Surgery report.
  • Survival rate: This is the percentage of patients still living after a set amount of years. In a study from The Journal of Thoracic Disease, the 5-year pneumonectomy survival rate was 38.5%.

Get a Free Lung Cancer Guide to learn more about how treatments like pneumonectomy can help you live longer and how to afford them.

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Benefits of Pneumonectomy for Lung Cancer Patients

A lung cancer pneumonectomy can be very beneficial to patients. The biggest benefit is the chance to improve long-term survival.

Many lung cancer patients who have received a pneumonectomy have lived for over 5 years after the procedure. Some even become long-term survivors, living for 20 years or more.

Side Effects & Complications of Pneumonectomy for Lung Cancer

Because a pneumonectomy involves removing a lung, patients are at a very high risk of complications both during and after the surgery.

These include:

  • Blood clots (pulmonary embolism)
  • Changes in heart rhythm
  • Excessive bleeding
  • Infections such as pneumonia
  • Respiratory failure
  • Shock

There is also a greater mortality risk with this surgery compared to other types of lung cancer treatment.

Factors like your age and other health problems will affect your risk for complications. Ask your health care provider about the potential side effects and complications of a pneumonectomy.

Lung Cancer Pneumonectomy With Other Treatments

Lung cancer doctors may prescribe other treatments along with a pneumonectomy to help patients live longer.

These lung cancer treatments include:

  • Chemotherapy may be given before a pneumonectomy and other surgeries. The most commonly used chemotherapy drug combination is cisplatin and etoposide (Vepesid®).
  • Immunotherapy uses substances to get the immune system to fight cancer. Examples of immunotherapy drugs include durvalumab (Imfinzi®), atezolizumab (Tecentriq®), and cemiplimab (Libtayo®).
  • Radiation therapy involves the use of high-energy beams to kill cancer, and it is often administered before a pneumonectomy.
  • Targeted therapy attacks proteins that affect how cancer cells divide, grow, and spread.

Your lung cancer specialist can review all treatments that you qualify for to determine which will work best for you.

Cost of Lung Cancer Pneumonectomy

The out-of-pocket cost of a lung cancer pneumonectomy is incredibly high. An extrapleural pneumonectomy costs approximately $62,000.

Even with insurance, the expenses of a pneumonectomy and other lung cancer treatments can be costly and bring financial uncertainty to families. However, there is hope for families affected by lung cancer.

With our team’s help, you or a loved one may be able to access lung cancer compensation to cover any expenses related to a lung cancer diagnosis.

Contact us now to see if we may be able to help you afford a lung cancer pneumonectomy and other treatment expenses.

Find Cancer Centers Offering Lung Cancer Pneumonectomy

A lung cancer pneumonectomy can potentially help you or someone you love live longer. Your health care team can determine if a pneumonectomy will be a good fit for your treatment plan.

However, after a lung cancer diagnosis, you may be concerned about how you’ll cover the costs of treatments like a pneumonectomy.

Thankfully, you don’t have to face lung cancer alone. Work with Lung Cancer Group to pursue the support and care you need and deserve.

Our team can help you:

  • Explore financial compensation options for medical expenses
  • Find emotional support during this trying time
  • Understand your treatment options

Call (877) 446-5767 now or Get a Free Lung Cancer Guide to learn about all the ways we can help you.

Lung Cancer Pneumonectomy FAQs

Can you live a normal life with one lung?

Yes, you can live a relatively normal life with one lung if you must undergo a pneumonectomy for lung cancer.

After one of your lungs is removed, your medical team will advise you on ways to strengthen your remaining lung to give you the best quality of life possible.

However, you can expect to feel tired and short of breath as your body adjusts to the loss of the lung.

The life expectancy of a person with lung cancer is roughly 47 months if they undergo a pneumonectomy, as noted in a report from Interactive Cardiovascular and Thoracic Surgery.

Factors like the patient’s overall health, lung cancer type, and more affect how long they’ll live.

A lobectomy only removes one lung lobe and all of the cancer that’s visible. It is much easier to recover from. By contrast, a pneumonectomy removes the entire lung affected by cancer. This surgery comes with a higher risk of complications and recovery takes a long time.

Contact us now to learn more about lung cancer surgeries like a pneumonectomy vs. lobectomy and how to afford any treatment costs you may face.

The 5-year survival rate following a lung cancer pneumonectomy is 38.5%, according to a study from The Journal of Thoracic Disease. This demonstrates that a pneumonectomy can help many patients become long-term survivors.

Some patients have even lived for 15-20 years or more following lung removal surgery.

Lung Cancer Group was established by a team of caring advocates so those with lung cancer and other asbestos-related diseases can get the help they deserve. Our site provides the most accurate and up-to-date information about lung cancer, its link to asbestos, and financial compensation available to patients. Contact us to learn more and get assistance.

  1. American Cancer Society. (2024, January 29). Surgery for non-small cell lung cancer. Retrieved January 6, 2025, from https://www.cancer.org/cancer/types/lung-cancer/treating-non-small-cell/surgery.html
  2. Brigham and Women’s Hospital. (n.d.). Pneumonectomy. Retrieved January 6, 2025, from https://www.brighamandwomens.org/medical-resources/pneumonectomy
  3. Brunswicker, A., et al. (2021, December 6). Pneumonectomy for primary lung cancer: contemporary outcomes, risk factors and model validation. Retrieved January 6, 2025, from https://pmc.ncbi.nlm.nih.gov/articles/PMC9159428/
  4. Cancer Canada. (n.d.). Treatments for stage 3 non–small cell lung cancer. Retrieved January 6, 2025, from https://cancer.ca/en/cancer-information/cancer-types/lung/treatment/stage-3
  5. City of Hope. (n.d.). Pneumonectomy. Retrieved January 6, 2025, from https://www.cancercenter.com/cancer-types/lung-cancer/treatments/pneumonectomy
  6. Cleveland Clinic. (n.d.). Pneumonectomy. Retrieved January 6, 2025, from https://my.clevelandclinic.org/health/treatments/25003-pneumonectomy
  7. Hopkins Medicine. (n.d.). Pneumonectomy. Retrieved January 6, 2025, from https://www.hopkinsmedicine.org/health/treatment-tests-and-therapies/pneumonectomy
  8. Lung.org. (n.d.). Thoracotomy. Retrieved January 6, 2025, from https://www.lung.org/lung-health-diseases/lung-procedures-and-tests/thoracotomy
  9. Moffitt Cancer Center. (n.d.). Pneumonectomy Surgery for Lung Cancer. Retrieved January 6, 2025, from https://www.moffitt.org/cancers/lung-cancer/treatment/surgery/pneumonectomy/
  10. Schussler, O., et al. (2022, February 10). Twenty-Year Survival of Patients Operated on for Non-Small-Cell Lung Cancer: The Impact of Tumor Stage and Patient-Related Parameters. Retrieved January 6, 2025, from https://pmc.ncbi.nlm.nih.gov/articles/PMC8870355/
  11. Skrzypczak, P., et al. (2019, April 4). Pneumonectomy – permanent injury or still effective method of treatment? Early and long-term results and quality of life after pneumonectomy due to non-small cell lung cancer. Retrieved January 6, 2025, from https://pmc.ncbi.nlm.nih.gov/articles/PMC6491376/
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