Mesothelioma Diagnosis
Getting a mesothelioma diagnosis before the cancer spreads is crucial to living longer. Doctors perform physical exams, imaging tests, and biopsies to confirm a diagnosis. If you’ve been diagnosed with mesothelioma, seek treatment as soon as possible. We can help you find top doctors to confirm a diagnosis and treat you.
How Is Mesothelioma Diagnosed?
Patients who have potential symptoms of mesothelioma should promptly see a doctor to get a diagnosis. Specialists can recommend tests to help diagnose this cancer, allowing patients to get top treatments sooner.
A diagnosis of malignant mesothelioma typically involves:
- Basic health assessment: A doctor will conduct a physical exam to check for symptoms like a cough or shortness of breath. Be sure to mention if you were ever exposed to asbestos, the only known cause of this cancer.
- Imaging tests: Computed tomography (CT) scans, X-rays, and more allow doctors to check for signs of mesothelioma inside the body.
- Blood tests: These allow doctors to identify specific indicators of mesothelioma and rule out other health issues.
- Biopsies: Doctors remove a sample of tissue or fluid and look for mesothelioma cells under a microscope. This is the only way to confirm a mesothelioma diagnosis.
Speak with a nurse now for help getting an accurate mesothelioma diagnosis and finding the best treatments for your case.
- Find Top Doctors and Treatments
- Connect You With Clinical Trials
- Answer Medical Questions

Amy Fair
20+ Years Helping
Mesothelioma Patients
Mesothelioma Tests for Diagnosis
Doctors use a wide range of tests to help confirm a mesothelioma diagnosis and rule out other conditions. A biopsy is the final and most conclusive test.
Learn about the different tests used in making a mesothelioma diagnosis below.
Imaging Scans for Mesothelioma
Imaging tests allow doctors to see the inside of your body and locate any abnormalities that could be causing possible mesothelioma symptoms.
Types of imaging tests for mesothelioma include:
- X-rays are the most common imaging scan. They provide a two-dimensional view of the body.
- CT scans create higher-resolution X-rays at cross-sections of either the whole body or part of it.
- Magnetic resonance imaging (MRI) scans use a strong magnet and a computer to create detailed pictures. MRI scans are typically better than CT scans for imaging soft tissues.
- Positron emission tomography (PET) scans use an injected radioactive tracer to locate mesothelioma cells in the body. They are often combined with CT scans.
These scans are completely painless, but some may require you to sit still for an hour or more.
Mesothelioma Blood Tests
Blood tests can help rule out other health conditions and show doctors mesothelioma biomarkers (signs of disease).
For example, MESOMARK is a mesothelioma blood test that looks for the protein SMRP in the blood. High levels of SMRP indicate that cancer cells are spreading at out-of-control rates.
Other blood panels can help doctors assess a patient’s expected health outcome with mesothelioma.
Biopsies to Confirm a Mesothelioma Diagnosis
A biopsy is the only way to confirm a mesothelioma diagnosis. It involves doctors removing fluid or tissue samples so a pathologist can review them for cancer under a microscope.
Common mesothelioma biopsy types include:
- Endoscopic biopsies involve inserting a long, flexible tube with a camera into the body. The doctor uses the endoscope to collect a biopsy sample. Types include thoracoscopy, laparoscopy, and mediastinoscopy.
- Fine-needle biopsies use a long needle linked to a syringe to gather sample cells for lab analysis. Fine-needle biopsy tests include thoracentesis, paracentesis, and pericardiocentesis.
- Liquid biopsies diagnose mesothelioma by allowing doctors to get cancer cells without taking tissue. However, these are often less accurate, so tissue biopsies are preferred.
- Open surgical biopsies involve making an incision in the chest (thoracotomy) or in the abdomen (laparotomy). The surgeon removes a larger tumor sample or takes out the whole tumor.
Open surgery biopsies are the most extensive, requiring anesthesia and a longer recovery. Endoscopic and fine-needle biopsies are far less invasive and may only require local anesthesia and less recovery time.
If you or a loved one was diagnosed with mesothelioma, connect with our registered nurses to find the best treatments for your case.
- Find Top Doctors and Treatments
- Connect You With Clinical Trials
- Answer Medical Questions



Amy Fair
20+ Years Helping
Mesothelioma Patients
Mesothelioma Diagnosis By Type
Mesothelioma can develop in different parts of the body. Doctors classify cases into specific types at the time of a mesothelioma diagnosis based on where tumors form. Learn about the mesothelioma types and the process to diagnose each below.
Pleural Mesothelioma Diagnosis

Pleural mesothelioma is the most commonly diagnosed type of mesothelioma. It affects the lining of the lungs (pleura) and makes up 75-80% of cases.
To diagnose this cancer, doctors start by noting any possible symptoms, including chest pain, a cough, and difficulty breathing. They’ll then take imaging scans of the chest to look for possible signs of mesothelioma.
Doctors can then extract a biopsy sample from a possibly cancerous mass in the chest to confirm a malignant pleural mesothelioma diagnosis.
Diagnosis of Peritoneal Mesothelioma

Peritoneal mesothelioma affects the lining of the abdomen (peritoneum) and is the second-most commonly diagnosed type of this cancer. It accounts for 10-15% of diagnoses.
Many cases of peritoneal mesothelioma start with abdominal bloating, pain, and weight and appetite loss. Doctors look for these symptoms before conducting imaging scans and biopsies to determine if a patient has peritoneal mesothelioma.
Diagnosing Rare Mesothelioma Types

There are also two very rare types of mesothelioma — pericardial and testicular.
Pericardial mesothelioma forms in the lining of the heart (pericardium), leading to symptoms like arrhythmia and chest pain. Testicular mesothelioma starts in the testicle lining and causes pain and swelling.
Doctors can use imaging scans and biopsies to diagnose both of these rare cancers. Pericardial mesothelioma is harder to diagnose, and most cases are only confirmed during autopsies.
Is Diagnosing Mesothelioma Difficult?
Reasons mesothelioma is difficult to diagnose include:
- Lack of specialization: Patients could see a general doctor who doesn’t have experience with mesothelioma, leading to misdiagnosis.
- Long latency period: It often takes 10-50 years for symptoms to form after initial asbestos exposure. Patients may delay seeing a doctor since mesothelioma may not be at the front of their minds.
- Rarity: Mesothelioma only affects about 3,000 people per year, so symptoms are often dismissed at first.
- Shared symptoms: Common mesothelioma symptoms like shortness of breath, cough, and weight loss could be mistaken for more common and less serious issues.
As a result of these issues, nearly 23% of mesothelioma cases are misdiagnosed at first, and many diagnoses take months to confirm.
“From the onset of symptoms, the diagnosis is an average time of about nine months.”
— Dr. Taylor Ripley, mesothelioma specialist
If you’re worried about mesothelioma, connect with a specialist as soon as possible. The sooner you get an accurate diagnosis, the faster you can get treatment for this aggressive cancer.
Mesothelioma Misdiagnosis
Mesothelioma misdiagnoses can vary depending on the type of cancer and which symptoms a patient is experiencing. Learn about common mesothelioma misdiagnoses in the table below.
Type of Mesothelioma | Common Misdiagnoses |
---|---|
Pleural mesothelioma | Lung cancer, bronchitis, cold or flu, lung disease, pneumonia |
Peritoneal mesothelioma | Ovarian cancer, hernia, gallstones, irritable bowel syndrome (IBS), Crohn’s disease |
Pericardial mesothelioma | Arrhythmia, heart disease, heart failure |
Testicular mesothelioma | Epididymitis (swelling or inflammation), hernia |
If you have been diagnosed with one of these conditions and your symptoms are continuing or worsening, you may need to get a second opinion. Contact our nurses now to get help finding a mesothelioma specialist near you.
What to Do After a Mesothelioma Diagnosis
If you or a loved one has received a mesothelioma diagnosis, follow these steps to get the treatment and help you need.
1. Consider a Second Opinion
Getting a second opinion following a mesothelioma diagnosis is helpful for a number of reasons.
With a mesothelioma second opinion, you’ll:
- Have confidence in your diagnosis
- Potentially get access to more treatment options
- Rule out any chance of misdiagnosis
Ideally, see a mesothelioma specialist if you haven’t already to ensure your second opinion is as accurate as possible.
“Just because someone’s an oncologist (cancer doctor) doesn’t mean they see a lot of mesothelioma. You want to see someone that’s a real mesothelioma specialist.”
— Dr. Raja Flores, mesothelioma specialist
2. Understand Your Mesothelioma Prognosis
When you are certain you have an accurate diagnosis, make sure you understand your mesothelioma prognosis (health outlook).
The average mesothelioma patient lives 12-21 months after a diagnosis. However, factors like cancer type, stage, and overall health can affect which treatments you receive and may allow you to live longer.
3. Get an Effective Treatment Plan
Getting mesothelioma treatment is the best way to potentially live longer after a diagnosis.
Common treatments for mesothelioma include:
- Surgery
- Chemotherapy
- Immunotherapy
- Radiation therapy
- Clinical trials testing new treatments
Your oncology team can tailor treatments to the specifics of your case, hopefully allowing you to improve your life expectancy.
4. Explore Compensation Options
Mesothelioma diagnostic tests and treatments can be expensive, costing $400,000 or more. You and your family may qualify for compensation through a mesothelioma lawsuit to cover expenses.
“We filed a mesothelioma lawsuit because we knew it was more than we could handle on our own. We came to realize it’s not going to be a cheap fight.”
— Alan Bonnin, mesothelioma patient
A mesothelioma lawsuit awards $1 million to $1.4 million on average, with some paying out much more.
Contact our team to learn if you can pursue financial compensation after a mesothelioma diagnosis.
Have You or a Loved One Been Diagnosed With Mesothelioma?
If you or a loved one is diagnosed with mesothelioma, it can bring a lot of anxiety. Cancer not only greatly affects your health, but can also lead to financial uncertainty due to treatment costs.
At Lung Cancer Group, we stand ready to help mesothelioma patients ensure their diagnosis is correct and access the medical care they deserve.
Work with our team to:
- Connect with doctors to get an accurate diagnosis
- Explore treatment options for mesothelioma
- Pursue financial compensation to cover expenses
Connect with a mesothelioma nurse right now or call (877) 446-5767 to get started.
Mesothelioma Diagnosis FAQs
What is the gold standard for diagnosing mesothelioma?
A procedure known as a biopsy is the gold standard for diagnosing mesothelioma. It’s the only way to know for certain if you have this cancer.
With this test, doctors remove a sample of tissue or fluid from a possibly cancerous growth or mass.
A pathologist then reviews the sample under a microscope to determine if a patient has mesothelioma or any other type of cancer.
What tests are done to diagnose mesothelioma?
Doctors use a basic health examination, imaging tests, biopsies, and sometimes blood tests to help diagnose mesothelioma.
The first tests include assessing symptoms and reviewing any potential exposure to asbestos. Specialists may then recommend imaging scans and blood tests to check for signs of mesothelioma.
If cancer is still suspected after those, a biopsy will be used to confirm a diagnosis.
What are the early warning signs of mesothelioma?
The early warning signs of mesothelioma may include:
- Difficulty breathing
- Fever
- Fluid buildup in the lung lining (pleural effusion)
- Shortness of breath
- Tiredness
Contact our mesothelioma nurses if you have these symptoms and a history of asbestos exposure. If eligible, they can connect you with mesothelioma specialists to confirm a diagnosis.
How is pleural mesothelioma diagnosed?
Doctors diagnose pleural mesothelioma by noting potential symptoms (a cough, shortness of breath, and chest pain) and then taking imaging scans of the chest.
If mesothelioma is still supected, doctors will remove a biopsy sample if a possibly cancerous tumor is found.
You can then start treatments to help you live as long as possible with pleural mesothelioma.
Does mesothelioma show up in blood work?
Mesothelioma biomarkers (or indicators of disease) may appear in blood tests. However, it is not possible to confirm a mesothelioma diagnosis with blood tests alone.
You’ll need to get a biopsy to know for certain whether you have mesothelioma or not.
Can a chest X-ray show mesothelioma?
A chest X-ray may be able to detect abnormal tissue or fluid buildup, which could signal mesothelioma.
Doctors will then perform a biopsy to examine the tissue in a lab and confirm a mesothelioma diagnosis.
Call (877) 446-5767 for help finding specialists who can diagnose and treat mesothelioma.